Key Features
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The Material Screening Kit is designed to help researchers identify the most suitable Smart MCs microcarrier family for their cell type and application before beginning process optimisation or scale-up.
Cell attachment, expansion, and harvesting performance can vary depending on the underlying microcarrier material and coating chemistry. To simplify the initial evaluation, the kit includes medium-stiffness versions of each Smart MCs microcarrier family, allowing researchers to compare material performance while keeping stiffness consistent across all samples.
For P2M microcarriers, both the animal-derived coating and the xeno-free/human protein-coated option are included, enabling comparison of coating chemistries alongside the different microcarrier materials.
By identifying the most suitable material and coating first, researchers can then optimise stiffness and other microcarrier properties within the selected platform, creating a more efficient and systematic development workflow.
The Material Screening Kit includes approximately 5,500 cmΒ² of total growth surface area across the included microcarrier families.
The Material Screening Kit contains medium-stiffness versions of the following Smart MCs microcarrier families:
Each microcarrier is supplied in its medium stiffness profile to provide a consistent basis for comparing material and coating performance using your own cells.
We recommend beginning all new microcarrier evaluations with the Material Screening Kit.
Evaluate the medium-stiffness versions of the Smart MCs microcarrier families using your own cells to determine which material and coating best support cell attachment, expansion, and recovery.
Once the preferred microcarrier family has been identified, evaluate Soft, Medium, and Hard stiffness profiles within that material to optimise cell performance.
Following material selection and stiffness optimisation, additional parametersβincluding particle size, surface charge, coating chemistry, and gradeβcan be tailored to suit your research or manufacturing workflow.
The Material Screening Kit allows researchers to compare the key characteristics of each Smart MCs microcarrier family before progressing to optimisation studies.
| Feature | P1 | X1 | P2 |
|---|---|---|---|
| Material | Synthetic polymer | Gelatin-based | Plant-based biopolymer |
| Dissolvable | No | Yes | Yes |
| Harvest Method | Standard separation | TrypLE or Trypsin | TrypLE + P2 Dissolving Buffer |
| Typical Dissolution | N/A | 20β30 minutes | <10 minutes |
| Coating Options | User-applied | Native gelatin | Animal-derived or xeno-free/human protein |
| Customisation | Size, stiffness, charge | Size, stiffness, coatings | Size, stiffness, coatings |
The complete technical comparison table is provided below.
The Material Screening Kit is suitable for:
Selecting the appropriate microcarrier family early can reduce development time and streamline process optimisation.
The Material Screening Kit enables researchers to:
| Kit Contents | X1M, P1M, P2M (Animal-Derived Coating), and P2M (Xeno-Free/Human Protein Coating) |
|---|---|
| Purpose | Initial screening of Smart MCs microcarrier families to identify the most suitable material for specific cell types and applications |
| Included Stiffness | Medium stiffness for all included microcarrier families |
| Total Available Surface Area | Approximately 5,500 cmΒ² |
| Particle Size | 160-260 Β΅m (customisable) |
| Material Platforms | Gelatin-based, Synthetic Polymer, and Plant-based Biopolymer |
| Surface Coating Options | Animal-derived and Xeno-Free/Human Protein-coated P2M microcarriers included |
| Material Form | Freeze-dried powder (supplied based on surface area) |
| Customisation Available | Soft, Medium, and Hard stiffness profiles, particle size, surface charge, coatings, and custom formulations available following material selection |
| Grade Availability | Research and GMP Grade |
| Certificate of Analysis | Provided for each included microcarrier |