The Impact of ECM Stiffness on MSC Differentiation – Why Stiffness Matters in Your Cell Culture
The mechanical properties of the extracellular matrix (ECM) play a crucial role in directing stem cell fate. According to the research by Na et al. (2024), published [...]
What ISCT Says About the Landmark FDA Approval of Allogeneic MSCs
The recent FDA approval of Mesoblast’s Ryoncil™, an allogeneic bone-marrow mesenchymal stromal cell (MSC) therapy, marks a significant milestone in regenerative medicine and cell therapy. This long-anticipated [...]
Monthly Scientific Webinar: Prof. Majid Ebrahimi Warkiani
We are excited to invite you to a special online seminar featuring Prof. Majid Ebrahimi Warkiani, an esteemed professor and researcher in microfluidics, organoid-on-a-chip, and IVF [...]
Smart MCs Partners with TCS Biosciences to Expand Access to Research Tools in the UK and Europe
We are excited to announce our partnership with TCS Biosciences Ltd, a trusted leader in laboratory reagents and test kits, now serving as the official distributor of [...]
Improving Adherent Cell Culture with Microcarriers in a Funnel-Type Fluidized Bed Reactor
Adherent cell culture is essential for many biotechnological applications, including stem cell expansion, vaccine production, and therapeutic manufacturing. A recent study by Seohyun Park, Hyunwoo Kim, [...]
January’2025 – Scientific Webinar: Prof. Steve Oh
We were honored to host Prof. Steve Oh for our January webinar, where he presented on:"Mesenchymal Stem Cell Therapies: Promises Fulfilled and Potential New Applications."Presentation Highlights:What are [...]
Happy New Year 2025 from Smart MCs! 🎉
As we close the chapter on 2024 and welcome the opportunities of 2025, we take a moment to reflect on the journey, celebrate achievements, and express [...]
FDA Approves First Mesenchymal Stromal Cell Therapy for Steroid-Refractory Acute Graft-Versus-Host Disease
The FDA has approved Ryoncil (remestemcel-L-rknd), the first mesenchymal stromal cell (MSC) therapy for steroid-refractory acute graft-versus-host disease (SR-aGVHD) in pediatric patients aged [...]
Serum-Free Cell Culture with Microbial Lysates: A Cost-Effective Solution for Scalable Growth
The cell culture industry is evolving to meet the growing demand for cultivated meat, also referred to as lab-grown or cultured meat. This innovative approach produces [...]
5 Essential Tips for Optimising Agitation in Your Microcarrier Culture
Agitation is a cornerstone of successful microcarrier-based cell culture, ensuring uniform mixing, nutrient distribution, and oxygenation. However, improper agitation can lead to issues such as aggregate [...]
Cultured Meat News: Vow’s Forged Gras
The future of food innovation is here, and companies like Vow are paving the way with revolutionary products like Forged Gras, a cultured twist on the controversial [...]
Why Customisable Microcarriers Are Essential for Scalable Cultured Meat Production
In the cultured meat industry, scalability and optimised cell culture processes are crucial for commercial success. Microcarriers (MCs) offer a reliable solution for achieving high cell densities, [...]
How iPSCs Are Changing the Game in Treating Corneal Endothelial Dysfunction
Corneal endothelial dysfunction (CED), which leads to vision impairment and corneal edema, has traditionally been managed through corneal transplants. Yet, with donor corneas in short supply, researchers [...]
Microbeads for Functional Food Ingredient Delivery
Did you know that microbeads or microcarriers can transform the delivery of functional food ingredients? These tiny, natural carriers, made from pectin and chitosan, are designed to [...]
5 Essential Tips to Promote Cell Attachment in Your Microcarrier Culture
As the demand for scalable cell culture systems increases, microcarrier cultures have become a popular choice for bioprocessing and tissue engineering. However, achieving strong cell attachment is [...]
Bioprocess Development for eCB-MSCs Expansion Using Microcarriers
Recent advancements in cell-based therapies highlight the potential of mesenchymal stromal cells (MSCs) to address various medical challenges. Equine cord blood-derived MSCs (eCB-MSCs), known for their regenerative [...]
Innovative Injectable Microcarrier-Hydrogel Composite for Dental Stem Cell Delivery and Tissue Regeneration
A new study introduces an advanced approach for dental tissue regeneration using an injectable microcarrier-hydrogel composite system. This method aims to address the limitations of conventional stem [...]
PhD Opportunity: Research in Animal-Free Hydrogels
In partnership with UNSW, we are excited to offer a fully funded PhD position focused on developing animal-free hydrogels for organoid culture and drug screening. This [...]
Top 12 Mistakes to AVOID When Using Microcarriers
Microcarrier culture is a powerful tool for large-scale cell production, but it requires careful attention to detail to avoid common mistakes that can compromise the quality and [...]
Advancements in Scalable SARS-CoV-2 Vaccine Production: The Role of Microcarrier-Based Cultures
In a recent publication, researchers have made significant advancements in the scalable production of viral vectors for SARS-CoV-2 vaccines. By leveraging microcarrier-based cell culture in stirred-tank bioreactors, [...]
Harnessing Microcarrier Culture for Large-Scale Screening of Active Compounds Acting on FGFR4 Using HEK293T Cells
One of the most significant advancements in drug discovery is the ability to screen bioactive compounds effectively and at scale. This is particularly important when using [...]
Cutting-Edge Microbioreactor Approach Enhances MSC Yield and Potency for Therapies
In a recent study, researchers have developed a novel microcarrier-microbioreactor platform that shows significant promise for improving the manufacturing process of mesenchymal stem and stromal cells [...]
Intensified Process Development for hiPSC-Based Therapeutics Demonstrates Improved Efficiency and Cell Quality
A recent study has shed light on a novel process intensification strategy for the expansion of human induced pluripotent stem cells (hiPSCs), which holds promise for [...]
Innovative Process for Large-Scale Expansion of Wharton’s Jelly Mesenchymal Stem Cells
Wharton’s jelly mesenchymal stem/stromal cells (WJMSCs) have gained significant attention due to their potential in immunomodulatory, anti-inflammatory, tissue repair, and regenerative therapies. These cells have shown promise [...]