Dengue fever is a serious mosquito-borne illness that affects hundreds of millions of people each year, particularly across Asia, the Pacific, and parts of Australia. There are four types of dengue virus, known as DENV1, DENV2, DENV3, and DENV4. A person can be infected with each type only once, and catching one doesn’t protect [...]
A pivotal shift toward human-relevant science, regulatory alignment, and the adoption of New Approach Methodologies (NAMs) In July 2025, the U.S. Food and Drug Administration (FDA) and the National Institutes of Health (NIH) jointly hosted the FDA-NIH Workshop: Reducing Animal Testing, a pivotal event in biomedical research policy. With broad participation from regulatory bodies, [...]
Smart MCs Pty Ltd is proud to announce its participation in a $900,000 research collaboration with the University of New South Wales (UNSW), supported by $900,000 in funding through the Australian Research Council (ARC) Linkage Program. This project is led by A/Prof. Christopher Marquis and Prof. Kris Kilian at UNSW. The project will focus on [...]
A new study led by Shiina Pasanen and colleagues, published in the Biotechnology Journal (2025), demonstrates a powerful approach to expanding human mesenchymal stem cells (hMSCs) using microcarrier-based systems. Although the team used custom-engineered microcarriers, the results strongly support the broader use of microcarriers in regenerative medicine and scalable cell manufacturing. The Challenge: Scaling [...]
Smart MCs is proud to share that our Chief Technology Officer, Dr. Lin Ding, presented at the 15th International NanoMedicine Conference (OzNanoMed 2025), held from 16–18 June at the Pier One Sydney Harbour Hotel in Sydney. On Tuesday, 17 June at 2:15 PM (AEST), Lin delivered a talk titled “Redraw Our Roadmap with Customer Voices: [...]
We were pleased to host A/Prof. Khoon Lim from the University of Sydney for our June webinar, where he presented on: Light-Activated Biomaterials as Bioinks for 3D Printing Presentation Highlights Hydrogel Development for 3D Bioprinting: A/Prof. Khoon Lim discussed his group's work on hydrogel-based biomaterials, focusing on gelatin and synthetic polymers like polyvinyl alcohol for [...]
We’re proud to announce that Smart MCs will be presenting a research poster at the ISSCR 2025 Annual Meeting, taking place 11–14 June 2025 at the Hong Kong Convention and Exhibition Centre. Organised by the International Society for Stem Cell Research, ISSCR 2025 is one of the world’s leading conferences for stem cell science [...]
A recent study by Ulpiano et al., published in Stem Cell Research & Therapy (2025), presents a fully scalable, Good Manufacturing Practice (GMP)-compliant platform for producing extracellular vesicles (EVs) derived from human mesenchymal stromal cells (MSCs). The platform uses microcarrier-based stirred-tank reactors (STRs) combined with advanced purification methods to enable continuous, large-scale production of [...]
Published in the Journal of Extracellular Vesicles, May 2024 Lead author: Dr. Gagandeep Kaur A study published in the Journal of Extracellular Vesicles reports that extracellular vesicles (EVs) derived from mesenchymal stem/stromal cells (MSCs) using microcarrier-based cultures are more effective in suppressing immune responses than those from conventional monolayer cultures. The researchers also found that [...]
As we age, hearing loss becomes more common—and frustrating. It’s not just about turning up the volume; it’s about tiny, delicate cells in our ears that get damaged and don’t grow back. Scientists are now exploring how stem cells and their “messenger bubbles” (called EVs) might actually help the body repair itself. This could [...]
