This whitepaper demonstrates the expansion of human Wharton’s Jelly mesenchymal stem cells (hMSCs) using Smart MCs’ X1 dissolvable microcarriers in a 100 mL bioreactor. The study showcases high cell attachment, robust cell proliferation, near-complete cell recovery, and maintenance of MSC surface marker expression following expansion, demonstrating the suitability of X1 microcarriers for scalable stem cell manufacturing workflows. Download the full whitepaper for the complete methodology, experimental data, and flow cytometry analysis.
Figure 1. Cell concentration and fold increase of human Wharton’s Jelly MSCs cultured on Smart MCs’ X1 dissolvable microcarriers in a 100 mL bioreactor over five days. The study demonstrates robust cell proliferation, reaching approximately 6 × 10⁵ cells/mL with a 17-fold increase in cell expansion by Day 5.
