X1 Microcarrier – MARC-145 Culture for PRRSV Production
Discover how Smart MCs' X1 dissolvable microcarriers support efficient expansion of MARC-145 cells and high-level PRRSV production for scalable vaccine manufacturing.
X1 Microcarrier – L929 Culture
Discover how Smart MCs' X1 dissolvable microcarriers support robust expansion of L929 mouse fibroblast cells in static and stirred bioreactor culture.
Peptide-Modified Hyaluronic Acid Microcarriers for Sustained Extracellular Vesicle Delivery
Figure 1. Overview of the peptide-functionalised hyaluronic acid microcarrier platform developed by Nie et al. Extracellular vesicles (EVs) derived from hepatocyte growth factor (HGF)-engineered mesenchymal stromal cells (MSCs) were captured using CP05-functionalised hyaluronic acid methacrylate (HAMA) microcarriers and evaluated as a sustained delivery platform for diabetic wound healing. Microcarriers are widely used [...]
Magnetic and Degradable Microcarriers for Drug Delivery and 3D Cell Culture
Figure 1. Overview of PEGDA-based magnetic hydrogel microcarrier fabrication and applications, including microfluidic bead generation, magnetic particle incorporation, UV photopolymerisation, homogeneous and Janus-type microcarrier formats, tunable degradation influenced by temperature and pH, and potential applications in soft robotics, 3D cell culture, cell transport, and drug delivery. Microcarriers are often described as small [...]
Why Are My Cells Not Attaching to the Microcarriers?
Figure 1. Uneven early cell attachment on microcarriers. Microscopy image showing variable cell attachment across microcarriers during the early seeding phase. Some carriers show visible cell attachment, while others remain sparsely populated, illustrating how early seeding conditions can affect attachment consistency. Poor cell attachment is one of the most frustrating issues in [...]
How to Expedite Microcarrier Dissolution While Maintaining Cell Quality
“Why is microcarrier dissolution taking longer than expected?” Microcarrier dissolution is a key step during harvest, but delays are usually linked to how the process is handled. In our experience, when the workflow is well understood and the steps are followed properly, dissolution is straightforward. When something isn’t quite right, or the process is [...]
FDA Reports One-Year Progress in Reducing Animal Testing in Drug Development
How the FDA’s roadmap is translating into real regulatory change In April 2026, the U.S. Food and Drug Administration (FDA) released a one-year progress update on its Roadmap to Reducing Animal Testing in Preclinical Safety Studies. The report highlights how early policy commitments are now being implemented across drug development, signalling a broader shift [...]
Microcarriers for Cultured Fat Production: Scaling Duck Fat in Bioreactors
A closer look at the research by Díaz-Maneh et al. (2026) The Problem: Scaling Fat Production for Cultured Meat When we talk about the future of food, cultured meat is often at the centre of the conversation. But there’s a secret ingredient that makes meat truly delicious: fat. It provides the flavour, the juicy texture, [...]
Smart MCs at the 2026 Advanced Therapies Congress in London
Smart MCs will be participating in the Advanced Therapies Congress 2026, taking place 17–18 March 2026 at ExCeL London. The event brings together researchers, biotech companies, and industry professionals working in the field of advanced therapy medicinal products (ATMPs).This year, Smart MCs will be represented by our UK & Europe distributor, TCS Biosciences.Presentation at the [...]
How to Minimise Cell Clumping During Microcarrier Culture
Microcarrier culture illustrating uneven cell seeding, where cells occupy some microcarriers and become confluent and clump, while others remain sparsely populated or empty. “Why are my cells forming clumps instead of evenly coating microcarriers?” Cell clumping is one of the most frequently encountered challenges in microcarrier-based culture, particularly when working with mesenchymal [...]