Small-scale microcarrier cultures play a crucial role in process development, allowing researchers to refine conditions before scaling up to larger bioreactors. However, managing small-scale cultures requires careful optimisation to ensure reliable and reproducible results. Here are five essential tips to enhance your small-scale microcarrier culture and set the foundation for successful scale-up. Use a Non-Adherent [...]
Agitation is a cornerstone of successful microcarrier-based cell culture, ensuring uniform mixing, nutrient distribution, and oxygenation. However, improper agitation can lead to issues such as aggregate formation or cell damage. Here are five focused tips to help you optimise agitation and achieve consistent results in your microcarrier culture. Know Your Context Different cell types [...]
As the demand for scalable cell culture systems increases, microcarrier cultures have become a popular choice for bioprocessing and tissue engineering. However, achieving strong cell attachment is critical for success. Whether you’re scaling up production or experimenting in the lab, these five key tips will help you enhance cell attachment and improve your outcomes. 1. [...]
Microcarrier culture is a powerful tool for large-scale cell production, but it requires careful attention to detail to avoid common mistakes that can compromise the quality and efficiency of your culture. From seeding to harvesting, each step presents its own challenges that, if not managed properly, can lead to suboptimal results.Inconsistent Seeding Due to Poor [...]
