Mesenchymal Stem Cell Isolation Protocol

The following protocols for isolating Mesenchymal Stem Cells (MSCs) are adapted and simplified by FUJIFILM Irvine Scientific from published reports. Please note that these protocols have not been validated by Smart MCs and are provided for reference purposes only. For additional MSC-related protocols and reagents, please visit the FUJIFILM Irvine Scientific website. You can [...]

By |2025-03-20T03:00:19+00:00March 20th, 2025|General News|0 Comments

Smart MCs Exhibiting at the 2025 Advanced Therapies Congress in London

We are pleased to announce that Smart MCs will be exhibiting at the Advanced Therapies Congress 2025, taking place on March 18-19, 2025, at ExCeL London. Recognised as Europe’s largest commercial cell and gene therapy event, this congress is a key meeting point for experts, researchers, and industry leaders who are shaping the future [...]

By |2025-03-17T05:10:33+00:00March 17th, 2025|General News|0 Comments

5 Essential Tips for Small-Scale Microcarrier Culture

Small-scale microcarrier cultures play a crucial role in process development, allowing researchers to refine conditions before scaling up to larger bioreactors. However, managing small-scale cultures requires careful optimisation to ensure reliable and reproducible results. Here are five essential tips to enhance your small-scale microcarrier culture and set the foundation for successful scale-up. Use a Non-Adherent [...]

By |2025-03-14T05:58:30+00:00March 14th, 2025|General News, Microcarrier Culture Tips|0 Comments

3D Scaffold-Derived Exosomes for Cartilage Repair

Cartilage injuries are difficult to treat due to the tissue’s limited ability to regenerate. Unlike other tissues, cartilage lacks blood vessels, nerves, and lymphatic supply, which are essential for delivering nutrients and immune cells to support healing. As a result, damaged cartilage often fails to repair itself, leading to degeneration and conditions such as [...]

By |2025-03-11T06:31:50+00:00March 11th, 2025|General News|0 Comments

The Impact of ECM Stiffness on MSC Differentiation – Why Stiffness Matters in Your Cell Culture

The mechanical properties of the extracellular matrix (ECM) play a crucial role in directing stem cell fate. According to the research by Na et al. (2024), published in Biomaterials, mesenchymal stem cells (MSCs) cultured on ECMs with different stiffness levels show significant differences in chromatin organisation and gene expression, ultimately driving lineage-specific differentiation.This study provides [...]

By |2025-02-17T01:52:43+00:00February 17th, 2025|General News|0 Comments

What ISCT Says About the Landmark FDA Approval of Allogeneic MSCs

The recent FDA approval of Mesoblast’s Ryoncil™, an allogeneic bone-marrow mesenchymal stromal cell (MSC) therapy, marks a significant milestone in regenerative medicine and cell therapy. This long-anticipated decision provides new hope for patients with steroid-refractory acute Graft-versus-Host Disease (GvHD) and sets a regulatory precedent for future MSC-based therapies worldwide. The International Society for Cell & [...]

By |2025-02-03T03:01:27+00:00February 3rd, 2025|General News|0 Comments

Smart MCs Partners with TCS Biosciences to Expand Access to Research Tools in the UK and Europe

We are excited to announce our partnership with TCS Biosciences Ltd, a trusted leader in laboratory reagents and test kits, now serving as the official distributor of Smart MCs products in the UK and Europe. This partnership will make our smart microcarriers, hydrogels, and microfluidics tools more accessible to researchers across these regions. About TCS [...]

By |2025-01-15T04:56:43+00:00January 15th, 2025|General News|0 Comments

Improving Adherent Cell Culture with Microcarriers in a Funnel-Type Fluidized Bed Reactor

Adherent cell culture is essential for many biotechnological applications, including stem cell expansion, vaccine production, and therapeutic manufacturing. A recent study by Seohyun Park, Hyunwoo Kim, and Duk Jae Oh, published in Biotechnology and Bioprocess Engineering (2024), introduces a funnel-type fluidized bed reactor that improves the efficiency and stability of microcarrier-based cell culture systems. [...]

By |2025-01-03T02:05:51+00:00January 3rd, 2025|General News|0 Comments

Happy New Year 2025 from Smart MCs! 🎉

As we close the chapter on 2024 and welcome the opportunities of 2025, we take a moment to reflect on the journey, celebrate achievements, and express our sincere gratitude to everyone who has been part of it. 2024: A Year of Innovation and Progress This past year has been a pivotal one for Smart [...]

By |2024-12-31T00:18:00+00:00December 31st, 2024|General News|0 Comments

FDA Approves First Mesenchymal Stromal Cell Therapy for Steroid-Refractory Acute Graft-Versus-Host Disease

The FDA has approved Ryoncil (remestemcel-L-rknd), the first mesenchymal stromal cell (MSC) therapy for steroid-refractory acute graft-versus-host disease (SR-aGVHD) in pediatric patients aged two months and older. This approval is a monumental milestone for regenerative medicine, offering a critical treatment option for a condition with limited alternatives and setting the stage [...]

By |2024-12-19T08:13:31+00:00December 19th, 2024|General News|0 Comments
Go to Top