RoosterBio, Inc. recently hosted a webinar titled Exploring MSC-EV Attributes: Analytical Comparison of Tissue Sources & Production Platforms. In this session, Dr. Elie Zakhem (Associate Director, Analytical Development and Services) and Dr. Stephen Lenzini (Senior Scientist) presented key insights on how different tissue sources and production platforms shape the characteristics of mesenchymal stem cell [...]
Smart MCs is a partner in the newly launched Additive Manufacturing Cooperative Research Centre (AMCRC) — a $271 million national initiative focused on transforming and strengthening Australia’s manufacturing capabilities through additive manufacturing (3D printing).The AMCRC brings together more than 100 organisations from across research, industry, and government. Some of the key partners include:BoeingCSIRORMIT UniversityUniversity of [...]
Smart MCs is proud to be a core partner in the $238 million SMART CRC (Solutions for Manufacturing Advanced Regenerative Therapies), a new national research centre hosted by The University of Queensland. This transformative initiative brings together more than 60 partners from across Australia’s research, biotech, and healthcare sectors to advance the way regenerative [...]
The United States Food and Drug Administration (FDA) recently announced a significant policy change. The FDA plans to phase out its requirement for animal testing in the safety evaluation of certain medicines, including monoclonal antibodies (mAbs). This change reflects the FDA’s effort to update drug testing practices with methods that are more relevant to human [...]
The following protocols for isolating Mesenchymal Stem Cells (MSCs) are adapted and simplified by FUJIFILM Irvine Scientific from published reports. Please note that these protocols have not been validated by Smart MCs and are provided for reference purposes only. For additional MSC-related protocols and reagents, please visit the FUJIFILM Irvine Scientific website. You can [...]
We are pleased to announce that Smart MCs will be exhibiting at the Advanced Therapies Congress 2025, taking place on March 18-19, 2025, at ExCeL London. Recognised as Europe’s largest commercial cell and gene therapy event, this congress is a key meeting point for experts, researchers, and industry leaders who are shaping the future [...]
Small-scale microcarrier cultures play a crucial role in process development, allowing researchers to refine conditions before scaling up to larger bioreactors. However, managing small-scale cultures requires careful optimisation to ensure reliable and reproducible results. Here are five essential tips to enhance your small-scale microcarrier culture and set the foundation for successful scale-up. Use a Non-Adherent [...]
Cartilage injuries are difficult to treat due to the tissue’s limited ability to regenerate. Unlike other tissues, cartilage lacks blood vessels, nerves, and lymphatic supply, which are essential for delivering nutrients and immune cells to support healing. As a result, damaged cartilage often fails to repair itself, leading to degeneration and conditions such as [...]
The mechanical properties of the extracellular matrix (ECM) play a crucial role in directing stem cell fate. According to the research by Na et al. (2024), published in Biomaterials, mesenchymal stem cells (MSCs) cultured on ECMs with different stiffness levels show significant differences in chromatin organisation and gene expression, ultimately driving lineage-specific differentiation.This study provides [...]
The recent FDA approval of Mesoblast’s Ryoncil™, an allogeneic bone-marrow mesenchymal stromal cell (MSC) therapy, marks a significant milestone in regenerative medicine and cell therapy. This long-anticipated decision provides new hope for patients with steroid-refractory acute Graft-versus-Host Disease (GvHD) and sets a regulatory precedent for future MSC-based therapies worldwide. The International Society for Cell & [...]
