Scalable Production of MSC-Derived Extracellular Vesicles Using Microcarrier-Based Stirred-Tank Reactors
A recent study by Ulpiano et al., published in Stem Cell Research & Therapy (2025), presents a fully scalable, Good Manufacturing Practice (GMP)-compliant platform for producing [...]
Study Finds Microcarrier-Cultured MSC-EVs Show Greater Potency Against Autoimmune Uveitis
Published in the Journal of Extracellular Vesicles, May 2024 Lead author: Dr. Gagandeep Kaur A study published in the Journal of Extracellular Vesicles reports that extracellular vesicles [...]
Treatment for Age-Related Hearing Loss: The Role of MSCs and Extracellular Vesicles
As we age, hearing loss becomes more common—and frustrating. It’s not just about turning up the volume; it’s about tiny, delicate cells in our ears that [...]
Smart MCs Poster at ISCT 2025 – New Orleons
We are excited to announce that our Scientific Advisor, Prof. Steve Oh, will be attending and presenting the latest research findings on Smart [...]
What We Learned from RoosterBio’s Webinar on MSC-Derived EVs
RoosterBio, Inc. recently hosted a webinar titled Exploring MSC-EV Attributes: Analytical Comparison of Tissue Sources & Production Platforms. In this session, Dr. Elie Zakhem (Associate Director, [...]
Smart MCs Partners with $271M AMCRC to Help Shape the Future of Australian Manufacturing
Smart MCs is a partner in the newly launched Additive Manufacturing Cooperative Research Centre (AMCRC) — a $271 million national initiative focused on transforming and strengthening Australia’s [...]
Smart MCs Joins $238M National Initiative to Power Australia’s Future of Regenerative Therapy Manufacturing
Smart MCs is proud to be a core partner in the $238 million SMART CRC (Solutions for Manufacturing Advanced Regenerative Therapies), a new national research centre [...]
FDA Plans to Phase Out Animal Testing for Monoclonal Antibodies — What It Means for the Future of Drug Development
The United States Food and Drug Administration (FDA) recently announced a significant policy change. The FDA plans to phase out its requirement for animal testing in the [...]
April’2025 – Scientific Webinar: A/Prof. Reza Nosrati
We were pleased to host A/Prof. Reza Nosrati from Monash University for our April webinar, where he presented on:From Engineering Reproduction to Navigating the Academic PathPresentation HighlightsPaper-based [...]
Mesenchymal Stem Cell Isolation Protocol
The following protocols for isolating Mesenchymal Stem Cells (MSCs) are adapted and simplified by FUJIFILM Irvine Scientific from published reports. Please note that these protocols have [...]
Smart MCs Exhibiting at the 2025 Advanced Therapies Congress in London
We are pleased to announce that Smart MCs will be exhibiting at the Advanced Therapies Congress 2025, taking place on March 18-19, 2025, at ExCeL London. [...]
5 Essential Tips for Small-Scale Microcarrier Culture
Small-scale microcarrier cultures play a crucial role in process development, allowing researchers to refine conditions before scaling up to larger bioreactors. However, managing small-scale cultures requires careful [...]
3D Scaffold-Derived Exosomes for Cartilage Repair
Cartilage injuries are difficult to treat due to the tissue’s limited ability to regenerate. Unlike other tissues, cartilage lacks blood vessels, nerves, and lymphatic supply, which [...]
March’2025 – Scientific Webinar: A/Prof. Lana McClements
We were pleased to host A/Prof. Lana McClements from the University of Technology Sydney for our March webinar, where she presented on:3D Modelling of Tissues Relevant to [...]
The Impact of ECM Stiffness on MSC Differentiation – Why Stiffness Matters in Your Cell Culture
The mechanical properties of the extracellular matrix (ECM) play a crucial role in directing stem cell fate. According to the research by Na et al. (2024), published [...]
What ISCT Says About the Landmark FDA Approval of Allogeneic MSCs
The recent FDA approval of Mesoblast’s Ryoncil™, an allogeneic bone-marrow mesenchymal stromal cell (MSC) therapy, marks a significant milestone in regenerative medicine and cell therapy. This long-anticipated [...]
February’2025 – Scientific Webinar: Prof. Majid Ebrahimi Warkiani
We were honored to host Prof. Majid Ebrahimi Warkiani for our February webinar, where he presented on: Microfluidic Systems for Cell Biology and Translation into Practice [...]
Smart MCs Partners with TCS Biosciences to Expand Access to Research Tools in the UK and Europe
We are excited to announce our partnership with TCS Biosciences Ltd, a trusted leader in laboratory reagents and test kits, now serving as the official distributor of [...]
Improving Adherent Cell Culture with Microcarriers in a Funnel-Type Fluidized Bed Reactor
Adherent cell culture is essential for many biotechnological applications, including stem cell expansion, vaccine production, and therapeutic manufacturing. A recent study by Seohyun Park, Hyunwoo Kim, [...]
January’2025 – Scientific Webinar: Prof. Steve Oh
We were honored to host Prof. Steve Oh for our January webinar, where he presented on:"Mesenchymal Stem Cell Therapies: Promises Fulfilled and Potential New Applications."Presentation Highlights:What are [...]
Happy New Year 2025 from Smart MCs! 🎉
As we close the chapter on 2024 and welcome the opportunities of 2025, we take a moment to reflect on the journey, celebrate achievements, and express [...]
FDA Approves First Mesenchymal Stromal Cell Therapy for Steroid-Refractory Acute Graft-Versus-Host Disease
The FDA has approved Ryoncil (remestemcel-L-rknd), the first mesenchymal stromal cell (MSC) therapy for steroid-refractory acute graft-versus-host disease (SR-aGVHD) in pediatric patients aged [...]
Serum-Free Cell Culture with Microbial Lysates: A Cost-Effective Solution for Scalable Growth
The cell culture industry is evolving to meet the growing demand for cultivated meat, also referred to as lab-grown or cultured meat. This innovative approach produces [...]
5 Essential Tips for Optimising Agitation in Your Microcarrier Culture
Agitation is a cornerstone of successful microcarrier-based cell culture, ensuring uniform mixing, nutrient distribution, and oxygenation. However, improper agitation can lead to issues such as aggregate [...]