Intensified Process Development for hiPSC-Based Therapeutics Demonstrates Improved Efficiency and Cell Quality
A recent study has shed light on a novel process intensification strategy for the expansion of human induced pluripotent stem cells (hiPSCs), which holds promise for [...]
Innovative Process for Large-Scale Expansion of Wharton’s Jelly Mesenchymal Stem Cells
Wharton’s jelly mesenchymal stem/stromal cells (WJMSCs) have gained significant attention due to their potential in immunomodulatory, anti-inflammatory, tissue repair, and regenerative therapies. These cells have shown promise [...]
Webinar Announcement: Bioprocessing and Artificial Intelligence in Cell Therapies – China’s Model
We are excited to announce that our Chief Scientific Advisor, Prof. Steve Oh, PhD, will be chairing an insightful webinar on "Bioprocessing and Artificial Intelligence in Cell [...]
High-yield Production of Inactivated Influenza H5N1 Vaccines from MDCK Cells using Microcarriers
Influenza viruses pose a significant threat to global health, with the potential to trigger pandemics. Vaccination remains the primary strategy to reduce illness and death during such [...]
Scaling Bovine Viral Vaccine Production with Innovative Bioreactor Technology
Check out this publication on how scaling bovine viral vaccine production can be enabled using Microcarriers: Vaccination remains the most effective method for controlling and preventing [...]
Advancing Gene Therapy: Enhancing AAV Vector Production with Microcarrier-Based Cultures
Adeno-associated virus (AAV) vectors are at the forefront of gene therapy, offering great potential for treating a variety of genetic disorders. However, a significant challenge in [...]
Smart MCs Poster at ISSCR Annual Meeting
Recently, Smart MCs' advisor, Prof. Steve Oh, attended the International Society for Stem Cell Research (ISSCR) Annual Meeting in Hamburg, Germany, on [...]
Impact of Extracellular Matrix Stiffness and Shear Stress on Myoblast Regeneration: New Insights from Recent Study
Introduction Recent research has shed light on the crucial factors affecting myoblast regeneration, a key process in muscle repair. Myoblasts, the precursor cells to muscle fibers, are [...]
Scalable Manufacturing of Gene-Modified Human Mesenchymal Stromal Cells with Microcarriers in Spinner Flasks
A recent publication titled "Scalable manufacturing of gene-modified human mesenchymal stromal cells with microcarriers in spinner flasks" in the Journal of Biotechnological Products and Process Engineering [...]
Exploring Cutting-Edge Cancer Treatment Models: The Role of Organoids and Organs-on-a-Chip
Cancer treatment faces a multitude of challenges, notably the variation in tumor behavior across different patients. This heterogeneity necessitates personalized approaches to treatment that can adapt [...]
Large-Scale Microcarrier Culture for Animal Viral Vaccine Production
Mandarin fish (Siniperca chuatsi) holds a crucial position in China's aquaculture industry. Yet, the persistent threats posed by Infectious Spleen and Kidney Necrosis Virus (ISKNV) and [...]
Smart MCs Announces New Partnership with Macquarie University
We are thrilled to share exciting news at Smart MCs! A pioneering partnership has been forged with Macquarie University, focusing on the development of an AI-based predictive [...]
Reconstructing the Heart with iPSCs: Insights and Innovations
Recent research spearheaded by Stanford scholars has shed light on the pioneering use of induced pluripotent stem cells (iPSCs) in cardiac tissue engineering (Link to Source [...]
Scalable Expansion of iPSCs Technology Using Microcarrier Cultures
Induced pluripotent stem cells (iPSCs) represent a cornerstone in regenerative medicine and biotechnological research. These versatile cells are generated from somatic cells and can differentiate into [...]
The Power of Functional Polymer Surfaces in Controlling Cell Behaviors
A recent review publication has shed light on the monumental potential of functional polymer surfaces in [...]
Enhancing the Palatability of Cultivated Meat: A Review
We are pleased to announce the publication of a significant review by our very own Dr. Christopher J. O'Keeffe, in collaboration with esteemed scientists from the University [...]
Revolutionising Vaccine Manufacturing: Insights from a Study on Microcarrier-Based Cell Culture
In the realm of biotechnology, the quest for more efficient methods to cultivate cells for vaccine production is ongoing. A recent paper titled "Seed Train Optimization [...]
Boosting Clinical Stem Cell Production: Smart MCs’ Leap Forward with TIA Grant
Sydney's biomaterials leader, Smart MCs PTY LTD, was selected fora notable grant from Therapeutic Innovation Australia (TIA) to explore the potential of novel microcarriers in scaling up [...]
Different morphologies of HEK293T cells in various types of culture dishes
Human embryonic kidney 293 (HEK293) cells are widely utilised in research and bioprocessing industries, yet scaling up their growth [...]
Smart MCs and University of Sydney Establish Collaboration on Stem Cell Production Project!
In a significant leap towards advancing stem cell research and biotechnology, Smart MCs PTY LTD is thrilled to announce its collaboration with Associate Professor Khoon Lim [...]
Microcarrier Innovations for Large-Scale MSCs Expansion
Microcarrier Innovations: Paving the Way for Large-Scale Mesenchymal Stromal Cell Expansion A recent review published in the Journal of Trends in Biotechnology highlights the critical advancements [...]
Efficient SARS-CoV-2 VSV Vaccine Production in Stirred-Tank Bioreactors
Publication Title: "High-Titer Manufacturing of SARS-CoV-2 Spike-Pseudotyped VSV in Stirred-Tank Bioreactors: A Leap in Vaccine Production Technology". DOI: 10.1016/j.omtm.2024.101189 In a significant advancement for vaccine production technology, [...]
AAV Production Using Microcarriers Shows Higher Viral Production Yield than Suspension Culture
Production of recombinant adeno-associated virus vectors using microcarrier culture of HEK293T cells The study conducted by Yongfa Lan, HaiRui Yang, and QingRui You from Obio Technology, [...]