PhD Opportunity: Research in Animal-Free Hydrogels
In partnership with UNSW, we are excited to offer a fully funded PhD position focused on developing animal-free hydrogels for organoid culture and drug screening. This [...]
Top 12 Mistakes to AVOID When Using Microcarriers
Microcarrier culture is a powerful tool for large-scale cell production, but it requires careful attention to detail to avoid common mistakes that can compromise the quality and [...]
Advancements in Scalable SARS-CoV-2 Vaccine Production: The Role of Microcarrier-Based Cultures
In a recent publication, researchers have made significant advancements in the scalable production of viral vectors for SARS-CoV-2 vaccines. By leveraging microcarrier-based cell culture in stirred-tank bioreactors, [...]
Harnessing Microcarrier Culture for Large-Scale Screening of Active Compounds Acting on FGFR4 Using HEK293T Cells
One of the most significant advancements in drug discovery is the ability to screen bioactive compounds effectively and at scale. This is particularly important when using [...]
Cutting-Edge Microbioreactor Approach Enhances MSC Yield and Potency for Therapies
In a recent study, researchers have developed a novel microcarrier-microbioreactor platform that shows significant promise for improving the manufacturing process of mesenchymal stem and stromal cells [...]
Intensified Process Development for hiPSC-Based Therapeutics Demonstrates Improved Efficiency and Cell Quality
A recent study has shed light on a novel process intensification strategy for the expansion of human induced pluripotent stem cells (hiPSCs), which holds promise for [...]
Innovative Process for Large-Scale Expansion of Wharton’s Jelly Mesenchymal Stem Cells
Wharton’s jelly mesenchymal stem/stromal cells (WJMSCs) have gained significant attention due to their potential in immunomodulatory, anti-inflammatory, tissue repair, and regenerative therapies. These cells have shown promise [...]
Webinar Announcement: Bioprocessing and Artificial Intelligence in Cell Therapies – China’s Model
We are excited to announce that our Chief Scientific Advisor, Prof. Steve Oh, PhD, will be chairing an insightful webinar on "Bioprocessing and Artificial Intelligence in Cell [...]
High-yield Production of Inactivated Influenza H5N1 Vaccines from MDCK Cells using Microcarriers
Influenza viruses pose a significant threat to global health, with the potential to trigger pandemics. Vaccination remains the primary strategy to reduce illness and death during such [...]
Scaling Bovine Viral Vaccine Production with Innovative Bioreactor Technology
Check out this publication on how scaling bovine viral vaccine production can be enabled using Microcarriers: Vaccination remains the most effective method for controlling and preventing [...]
Advancing Gene Therapy: Enhancing AAV Vector Production with Microcarrier-Based Cultures
Adeno-associated virus (AAV) vectors are at the forefront of gene therapy, offering great potential for treating a variety of genetic disorders. However, a significant challenge in [...]
Smart MCs Poster at ISSCR Annual Meeting
Recently, Smart MCs' advisor, Prof. Steve Oh, attended the International Society for Stem Cell Research (ISSCR) Annual Meeting in Hamburg, Germany, on [...]
Impact of Extracellular Matrix Stiffness and Shear Stress on Myoblast Regeneration: New Insights from Recent Study
Introduction Recent research has shed light on the crucial factors affecting myoblast regeneration, a key process in muscle repair. Myoblasts, the precursor cells to muscle fibers, are [...]
Scalable Manufacturing of Gene-Modified Human Mesenchymal Stromal Cells with Microcarriers in Spinner Flasks
A recent publication titled "Scalable manufacturing of gene-modified human mesenchymal stromal cells with microcarriers in spinner flasks" in the Journal of Biotechnological Products and Process Engineering [...]
Exploring Cutting-Edge Cancer Treatment Models: The Role of Organoids and Organs-on-a-Chip
Cancer treatment faces a multitude of challenges, notably the variation in tumor behavior across different patients. This heterogeneity necessitates personalized approaches to treatment that can adapt [...]
Large-Scale Microcarrier Culture for Animal Viral Vaccine Production
Mandarin fish (Siniperca chuatsi) holds a crucial position in China's aquaculture industry. Yet, the persistent threats posed by Infectious Spleen and Kidney Necrosis Virus (ISKNV) and [...]
Smart MCs Announces New Partnership with Macquarie University
We are thrilled to share exciting news at Smart MCs! A pioneering partnership has been forged with Macquarie University, focusing on the development of an AI-based predictive [...]
Reconstructing the Heart with iPSCs: Insights and Innovations
Recent research spearheaded by Stanford scholars has shed light on the pioneering use of induced pluripotent stem cells (iPSCs) in cardiac tissue engineering (Link to Source [...]
Scalable Expansion of iPSCs Technology Using Microcarrier Cultures
Induced pluripotent stem cells (iPSCs) represent a cornerstone in regenerative medicine and biotechnological research. These versatile cells are generated from somatic cells and can differentiate into [...]
The Power of Functional Polymer Surfaces in Controlling Cell Behaviors
A recent review publication has shed light on the monumental potential of functional polymer surfaces in [...]
Enhancing the Palatability of Cultivated Meat: A Review
We are pleased to announce the publication of a significant review by our very own Dr. Christopher J. O'Keeffe, in collaboration with esteemed scientists from the University [...]
Revolutionising Vaccine Manufacturing: Insights from a Study on Microcarrier-Based Cell Culture
In the realm of biotechnology, the quest for more efficient methods to cultivate cells for vaccine production is ongoing. A recent paper titled "Seed Train Optimization [...]
Boosting Clinical Stem Cell Production: Smart MCs’ Leap Forward with TIA Grant
Sydney's biomaterials leader, Smart MCs PTY LTD, was selected fora notable grant from Therapeutic Innovation Australia (TIA) to explore the potential of novel microcarriers in scaling up [...]
