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Expanding Stem Cells Efficiently: New Research Shows Why Microcarriers Matter

A new study led by Shiina Pasanen and colleagues, published in the Biotechnology Journal (2025), demonstrates a powerful approach to expanding human mesenchymal stem cells (hMSCs) using microcarrier-based systems. Although the team used custom-engineered microcarriers, the results strongly support the broader use of microcarriers in regenerative medicine and scalable cell manufacturing. The Challenge: Scaling [...]

By |2025-06-20T07:38:15+00:00June 20th, 2025|General News|0 Comments

Smart MCs to Present on Microcarrier Commercialisation at OzNanoMed 2025

Smart MCs is proud to share that our Chief Technology Officer, Dr. Lin Ding, presented at the 15th International NanoMedicine Conference (OzNanoMed 2025), held from 16–18 June at the Pier One Sydney Harbour Hotel in Sydney. On Tuesday, 17 June at 2:15 PM (AEST), Lin delivered a talk titled “Redraw Our Roadmap with Customer Voices: [...]

By |2025-06-17T06:57:42+00:00June 16th, 2025|General News|0 Comments

June’2025 – Scientific Webinar: A/Prof. Khoon Lim

Smart MCS invites you to our next Scientific Webinar, featuring A/Prof. Khoon Lim from the University of Sydney. This session will explore the essential material design strategies that make bioprinting possible — from polymer chemistries to crosslinking systems. A/Prof. Lim will provide a deep dive into the chemistry behind bioinks, and how they enable cell-safe, [...]

By |2025-06-12T01:59:38+00:00June 12th, 2025|Webinars|0 Comments

Smart MCs to Present Poster at ISSCR 2025 in Hong Kong

We’re proud to announce that Smart MCs will be presenting a research poster at the ISSCR 2025 Annual Meeting, taking place 11–14 June 2025 at the Hong Kong Convention and Exhibition Centre. Organised by the International Society for Stem Cell Research, ISSCR 2025 is one of the world’s leading conferences for stem cell science [...]

By |2025-06-09T01:40:11+00:00June 9th, 2025|General News|0 Comments

Scalable Production of MSC-Derived Extracellular Vesicles Using Microcarrier-Based Stirred-Tank Reactors

A recent study by Ulpiano et al., published in Stem Cell Research & Therapy (2025), presents a fully scalable, Good Manufacturing Practice (GMP)-compliant platform for producing extracellular vesicles (EVs) derived from human mesenchymal stromal cells (MSCs). The platform uses microcarrier-based stirred-tank reactors (STRs) combined with advanced purification methods to enable continuous, large-scale production of [...]

By |2025-05-20T08:29:25+00:00May 20th, 2025|General News|0 Comments

Study Finds Microcarrier-Cultured MSC-EVs Show Greater Potency Against Autoimmune Uveitis

Published in the Journal of Extracellular Vesicles, May 2024 Lead author: Dr. Gagandeep Kaur A study published in the Journal of Extracellular Vesicles reports that extracellular vesicles (EVs) derived from mesenchymal stem/stromal cells (MSCs) using microcarrier-based cultures are more effective in suppressing immune responses than those from conventional monolayer cultures. The researchers also found that [...]

By |2025-05-15T09:05:06+00:00May 15th, 2025|General News|0 Comments

Treatment for Age-Related Hearing Loss: The Role of MSCs and Extracellular Vesicles

As we age, hearing loss becomes more common—and frustrating. It’s not just about turning up the volume; it’s about tiny, delicate cells in our ears that get damaged and don’t grow back. Scientists are now exploring how stem cells and their “messenger bubbles” (called EVs) might actually help the body repair itself. This could [...]

By |2025-04-25T06:28:18+00:00May 5th, 2025|General News|0 Comments

What We Learned from RoosterBio’s Webinar on MSC-Derived EVs

RoosterBio, Inc. recently hosted a webinar titled Exploring MSC-EV Attributes: Analytical Comparison of Tissue Sources & Production Platforms. In this session, Dr. Elie Zakhem (Associate Director, Analytical Development and Services) and Dr. Stephen Lenzini (Senior Scientist) presented key insights on how different tissue sources and production platforms shape the characteristics of mesenchymal stem cell [...]

By |2025-04-25T06:26:46+00:00May 2nd, 2025|General News|0 Comments

Smart MCs Partners with $271M AMCRC to Help Shape the Future of Australian Manufacturing

Smart MCs is a partner in the newly launched Additive Manufacturing Cooperative Research Centre (AMCRC) — a $271 million national initiative focused on transforming and strengthening Australia’s manufacturing capabilities through additive manufacturing (3D printing).The AMCRC brings together more than 100 organisations from across research, industry, and government. Some of the key partners include:BoeingCSIRORMIT UniversityUniversity of [...]

By |2025-04-25T06:20:30+00:00April 28th, 2025|General News|0 Comments

Smart MCs Joins $238M National Initiative to Power Australia’s Future of Regenerative Therapy Manufacturing

Smart MCs is proud to be a core partner in the $238 million SMART CRC (Solutions for Manufacturing Advanced Regenerative Therapies), a new national research centre hosted by The University of Queensland. This transformative initiative brings together more than 60 partners from across Australia’s research, biotech, and healthcare sectors to advance the way regenerative [...]

By |2025-04-24T08:27:26+00:00April 24th, 2025|General News|0 Comments
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