The FDA has approved Ryoncil (remestemcel-L-rknd), the first mesenchymal stromal cell (MSC) therapy for steroid-refractory acute graft-versus-host disease (SR-aGVHD) in pediatric patients aged two months and older. This approval is a monumental milestone for regenerative medicine, offering a critical treatment option for a condition with limited alternatives and setting the stage [...]
The cell culture industry is evolving to meet the growing demand for cultivated meat, also referred to as lab-grown or cultured meat. This innovative approach produces meat by growing animal cells in controlled environments, bypassing the need for traditional farming. Cultivated meat has the potential to address key global challenges, including reducing greenhouse gas [...]
Agitation is a cornerstone of successful microcarrier-based cell culture, ensuring uniform mixing, nutrient distribution, and oxygenation. However, improper agitation can lead to issues such as aggregate formation or cell damage. Here are five focused tips to help you optimise agitation and achieve consistent results in your microcarrier culture. Know Your Context Different cell types [...]
The future of food innovation is here, and companies like Vow are paving the way with revolutionary products like Forged Gras, a cultured twist on the controversial delicacy foie gras. Launched in New York City, Forged Gras is bringing foie gras back to menus worldwide—ethically and sustainably. This milestone highlights how cultured meat is evolving, [...]
In the cultured meat industry, scalability and optimised cell culture processes are crucial for commercial success. Microcarriers (MCs) offer a reliable solution for achieving high cell densities, making them essential in producing large volumes of cells needed for cultivated meat. However, customization of microcarriers is key to maximising their effectiveness, particularly when working in serum-free [...]
Corneal endothelial dysfunction (CED), which leads to vision impairment and corneal edema, has traditionally been managed through corneal transplants. Yet, with donor corneas in short supply, researchers have been exploring alternative solutions. Now, induced pluripotent stem cells (iPSCs) are emerging as a promising source of corneal endothelial cells (CECs), offering a renewable approach that could [...]
Did you know that microbeads or microcarriers can transform the delivery of functional food ingredients? These tiny, natural carriers, made from pectin and chitosan, are designed to protect sensitive nutrients like probiotics, vitamins, and other bioactive compounds from the harsh conditions of the stomach. A recent study published in Foods (2024) reveals the potential of [...]
Recent advancements in cell-based therapies highlight the potential of mesenchymal stromal cells (MSCs) to address various medical challenges. Equine cord blood-derived MSCs (eCB-MSCs), known for their regenerative and immunomodulatory abilities, are particularly promising for veterinary applications. Efficient expansion of these cells is crucial to meet therapeutic demands, a task not adequately met by traditional static [...]
A new study introduces an advanced approach for dental tissue regeneration using an injectable microcarrier-hydrogel composite system. This method aims to address the limitations of conventional stem cell therapies, particularly the challenges of low cell viability and poor integration after transplantation. By combining dental pulp stem cells (DPSCs) with a composite [...]
In partnership with UNSW, we are excited to offer a fully funded PhD position focused on developing animal-free hydrogels for organoid culture and drug screening. This multidisciplinary project integrates biochemistry and cell biology to create innovative synthetic and natural polymer hydrogels, contributing to advancements in regenerative medicine and pharmacology. Project Overview The PhD candidate [...]
