Adherent cell culture is essential for many biotechnological applications, including stem cell expansion, vaccine production, and therapeutic manufacturing. A recent study by Seohyun Park, Hyunwoo Kim, and Duk Jae Oh, published in Biotechnology and Bioprocess Engineering (2024), introduces a funnel-type fluidized bed reactor that improves the efficiency and stability of microcarrier-based cell culture systems. [...]

As we close the chapter on 2024 and welcome the opportunities of 2025, we take a moment to reflect on the journey, celebrate achievements, and express our sincere gratitude to everyone who has been part of it. 2024: A Year of Innovation and Progress This past year has been a pivotal one for Smart [...]

The FDA has approved Ryoncil (remestemcel-L-rknd), the first mesenchymal stromal cell (MSC) therapy for steroid-refractory acute graft-versus-host disease (SR-aGVHD) in pediatric patients aged two months and older. This approval is a monumental milestone for regenerative medicine, offering a critical treatment option for a condition with limited alternatives and setting the stage [...]

The cell culture industry is evolving to meet the growing demand for cultivated meat, also referred to as lab-grown or cultured meat. This innovative approach produces meat by growing animal cells in controlled environments, bypassing the need for traditional farming. Cultivated meat has the potential to address key global challenges, including reducing greenhouse gas [...]

The future of food innovation is here, and companies like Vow are paving the way with revolutionary products like Forged Gras, a cultured twist on the controversial delicacy foie gras. Launched in New York City, Forged Gras is bringing foie gras back to menus worldwide—ethically and sustainably. This milestone highlights how cultured meat is evolving, [...]

In the cultured meat industry, scalability and optimised cell culture processes are crucial for commercial success. Microcarriers (MCs) offer a reliable solution for achieving high cell densities, making them essential in producing large volumes of cells needed for cultivated meat. However, customization of microcarriers is key to maximising their effectiveness, particularly when working in serum-free [...]

Corneal endothelial dysfunction (CED), which leads to vision impairment and corneal edema, has traditionally been managed through corneal transplants. Yet, with donor corneas in short supply, researchers have been exploring alternative solutions. Now, induced pluripotent stem cells (iPSCs) are emerging as a promising source of corneal endothelial cells (CECs), offering a renewable approach that could [...]

Did you know that microbeads or microcarriers can transform the delivery of functional food ingredients? These tiny, natural carriers, made from pectin and chitosan, are designed to protect sensitive nutrients like probiotics, vitamins, and other bioactive compounds from the harsh conditions of the stomach. A recent study published in Foods (2024) reveals the potential of [...]

Recent advancements in cell-based therapies highlight the potential of mesenchymal stromal cells (MSCs) to address various medical challenges. Equine cord blood-derived MSCs (eCB-MSCs), known for their regenerative and immunomodulatory abilities, are particularly promising for veterinary applications. Efficient expansion of these cells is crucial to meet therapeutic demands, a task not adequately met by traditional static [...]