Smart MCS invites you to our next Scientific Webinar, featuring A/Prof. Lana McClements from the University of Technology Sydney. This session will focus on 3D bioprinting and microfluidics for modeling placental, vascular, and cardiac tissues, with applications in reproductive and cardiovascular disease research.

Webinar Details

Date: Monday, 31 March 2025
Time: 7:00 PM (AEDT) – Sydney, Australia

Location: Zoom

For attendees in other time zones:

  • 4:00 PM (SGT) – Singapore
  • 8:00 AM (GMT) – London, UK
  • 12:00 AM (PST) – Los Angeles, USA

Register now by filling out the form below.

Presentation Highlights

  • 3D Bioprinted Placental Organoids – Used to model placental development and pregnancy complications
  • Placenta-on-a-Chip – A microfluidic system replicating placental function and preeclampsia
  • 3D Cardiac Spheroids – Investigating cardiovascular disease in pregnancy and women’s heart health
  • Vasculature-on-a-Chip – Simulating endothelial dysfunction and vascular diseases

Research Applications

  • Identifying disease mechanisms in cardio-obstetrics disorders
  • Biomarker discovery for early diagnosis and risk prediction
  • Testing new therapeutic approaches for reproductive and cardiovascular diseases

Full Abstract

We have developed robust, low-cost and reproducible 3D in vitro models of placental, vascular and cardiac tissues. 3D bioprinted placental organoids, placenta-on-a-chip, vasculature-on-a-chip, and 3D cardiac spheroid models were utilized to identify key pathogenic mechanisms, biomarkers, and test new therapies for a range of cardio-obstetrics disorders.

This talk will present the development, validation, and characterization of the first-trimester trophoblast 3D bioprinted organoid models of placental tissue and 3D cardiac spheroid models of women’s heart health, using various extracellular matrices and 3D modeling approaches.

Furthermore, 3D microfluidic models of placenta-on-a-chip and vasculature-on-a-chip will also be described, modeling placental development and endothelial dysfunction, respectively.

Finally, the translation of results related to novel molecular insights, biomarker identification, and treatment strategies for reproductive and cardiovascular diseases will be presented.

About A/Prof. Lana McClements

Lana is a Senior Lecturer and Principal Investigator at the University of Technology Sydney, leading research in pregnancy-related cardiovascular diseases and biomarker discovery.

Research and Professional Background

  • Heart Foundation Future Leader Fellow
  • Newcastle Reproduction Emerging Research Leader Award recipient
  • BUPA Foundation Emerging Health Researcher commendation
  • Leads bioprinted models for placental and cardiovascular research
  • Research interests include stem cell biology, endothelial dysfunction, and oxidative stress

Why Attend?

  • Learn about 3D modeling approaches for reproductive health research
  • Understand how bioprinting and microfluidic technologies are applied in disease modeling
  • Engage in a live Q&A session with an expert in cardio-obstetrics and women’s health

Register now by completing the form below.

For inquiries about 3D cell culture and microfluidic devices, visit our Product Page or contact us at info@smartmcs.com.au.

This event is part of the Smart MCS Webinar Series, providing insights into bioprocessing, cell biology, and biomedical research.

Register Now for Smart MCs Monthly Scientific Webinars
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