Why use HAMA?
Hyaluronic acid is a key component of the extracellular matrix, especially in soft tissues. Because of this, HAMA is often used when a more biologically relevant and hydrated environment is needed.
Once exposed to light, HAMA forms a hydrogel that supports:
- Cell proliferation and migration
- Tissue-like structure formation
- Soft and highly hydrated matrices
It’s commonly used in:
- 3D cell culture
- Tissue engineering
- 3D bioprinting
- Drug delivery and release studies
Available HAMA Hydrogel Options
Smart MCs offers Hyaluronic Acid Methacryloyl (HAMA) hydrogel in two molecular weight options. Each HAMA product is supplied as a set with LAP photoinitiator included.
HAMA-150K Set
Includes:
- 0.5 g HAMA-150K hydrogel
- 0.025 g LAP photoinitiator
HAMA-150K has a molecular weight range of approximately 100–200 kDa. It has medium viscosity and is suitable for printable hydrogels, structural constructs, tissue models, and general 3D culture applications.
HAMA-400K Set
Includes:
- 0.2 g HAMA-400K hydrogel
- 0.025 g LAP photoinitiator
HAMA-400K has a molecular weight range of approximately 300–400 kDa. It has higher viscosity and forms softer hydrogels, making it suitable for soft tissue models, injectable systems, drug delivery, and composite hydrogels.
Both options are supplied as white, sponge-like materials and can be used alone or combined with hydrogels such as GelMA.
Performance
HAMA is designed to be flexible and easy to work with across different research workflows.
- Rapid gelation under visible light (typically within seconds)
- Tunable stiffness depending on concentration and formulation
- Wide mechanical range from very soft to more structured hydrogels
- Suitable for both extrusion and light-based 3D printing
Detailed characterisation data is available on request.
Custom options
We can modify HAMA depending on your application, including:
- Peptide-functionalised hydrogels
- Composite hydrogels (e.g. GelMA + HAMA systems)
- Tailored mechanical or biological properties
