Hyaluronic Acid Methacryloyl (HAMA) Hydrogel

Why use HAMA?

Hyaluronic acid is a key component of the extracellular matrix, especially in soft tissues. Because of this, HAMA is often used when a more biologically relevant and hydrated environment is needed.

Once exposed to light, HAMA forms a hydrogel that supports:

• Cell proliferation and migration
• Tissue-like structure formation
• Soft and highly hydrated matrices

It’s commonly used in:

• 3D cell culture
• Tissue engineering
• 3D bioprinting
• Drug delivery and release studies

Available options

We offer HAMA in different molecular weight ranges to suit different applications:

• HAMA-150K (medium molecular weight)
  Easier to handle and print, with a wider stiffness range. Suitable for scaffold-based applications and general tissue models.
• HAMA-400K (high molecular weight)
  More viscous with softer mechanical properties. Better suited for softer tissues, injectable systems, or when higher shape retention is needed.

Both options are supplied as a white, sponge-like material and can be used on their own or combined with other hydrogels such as GelMA.

Performance

HAMA is designed to be flexible and easy to work with across different research workflows.

• Rapid gelation under visible light (typically within seconds)
• Tunable stiffness depending on concentration and formulation
• Wide mechanical range from very soft to more structured hydrogels
• Suitable for both extrusion and light-based 3D printing

Detailed characterisation data is available on request.

Custom options

We can modify HAMA depending on your application, including:

• Peptide-functionalised hydrogels
• Composite hydrogels (e.g. GelMA + HAMA systems)
• Tailored mechanical or biological properties