Alginate Methacryloyl (AlgMA) Hydrogel

Alginate Methacryloyl (AlgMA) is a photocrosslinkable hydrogel used in 3D cell culture, tissue engineering, and bioprinting. It is derived from sodium alginate and modified to enable light-based crosslinking, offering a more controlled and uniform alternative to traditional ionic (calcium) gelation.

At Smart MCs, AlgMA is supplied with a compatible photoinitiator (LAP), allowing fast and consistent hydrogel formation under UV or visible light.

For research use only. Not intended for human clinical applications.

 

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Description

Why use AlgMA?

Alginate is widely used in biomaterials due to its stability and biocompatibility. By modifying it into AlgMA, researchers gain more control over gel formation and structure.

Compared to traditional alginate gels, AlgMA offers:

  • More uniform and reproducible hydrogel formation
  • Light-controlled crosslinking instead of ionic curing
  • Better control over structure and shape
  • Functional groups for further modification

It’s commonly used for:

  • 3D cell encapsulation
  • Tissue engineering scaffolds
  • 3D bioprinting
  • Drug delivery and release systems

Available options

We offer AlgMA in two molecular weight ranges:

  • AlgMA-50K (lower molecular weight)
    Easier to handle and provides higher stiffness at increased concentrations. Suitable for applications where structure and mechanical strength are important.
  • AlgMA-300K (higher molecular weight)
    More viscous and forms softer, more flexible hydrogels. Often used for cell encapsulation and softer tissue models.

Both variants are supplied as a white, sponge-like material and can be used alone or combined with other hydrogels such as GelMA or HAMA.

Performance

AlgMA is designed for consistent performance across different applications.

  • Rapid gelation under light (typically within ~20 seconds)
  • Tunable mechanical properties depending on formulation
  • Wide stiffness range from soft to more structured gels
  • Good printability and shape retention for 3D constructs

Detailed characterisation data is available on request.

Custom options

We can modify AlgMA depending on your application, including:

  • Peptide-functionalised hydrogels
  • Composite hydrogels (e.g. AlgMA + GelMA systems)
  • Tailored mechanical or structural properties
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Additional information

Material

Alginate Methacryloyl (AlgMA)

Grade

Research use only

Appearance

White, sponge-like (all variants: AlgMA-50K & AlgMA-300K)

Digestibility

Non-enzymatically degradable

Surface charge

Customisable

Certificate of Analysis

Available upon request

SDS

Available upon request

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