Smart MCs provides organ-on-a-chip (OoC) devices designed to model tissue microenvironments using microfluidic systems. These lab-on-a-chip platforms enable controlled fluid flow, cell–cell interactions, and integration with extracellular matrix (ECM) hydrogels for in vitro studies.
Organ-on-a-chip devices are used to study physiological responses, disease mechanisms, and interactions with pharmaceutical compounds under controlled conditions.
Organ-on-a-chip systems support a wide range of research applications:
The organ-on-a-chip approaches are supported by published research demonstrating microfluidic tissue models and device fabrication methods:
A rapidly prototyped lung-on-a-chip model using 3D-printed molds
Organ-on-a-Chip (2020)
https://doi.org/10.1016/j.ooc.2020.100001
This study presents a lung-on-a-chip model fabricated using 3D-printed molds for PDMS casting, enabling rapid and low-cost device prototyping. The system supports air–liquid interface culture under dynamic conditions, allowing cells to develop 3D morphology, maintain barrier integrity, and exhibit functional characteristics relevant to pulmonary tissue.
The device was used to evaluate responses to cigarette smoke extract and anti-inflammatory treatment, demonstrating its application in drug testing, toxicology, and respiratory research.
| ApplicationsProduct Type | Organ-on-a-chip (microfluidic device) |
|---|---|
| System Type | Multi-channel microfluidic platform |
| Culture Type | 2D and 3D cell culture (hydrogel compatible) |
| Flow Type | Laminar flow, perfusion-based systems |
| Applications | Tissue modelling, drug testing, biological research |
| Sterility | Autoclave and gamma irradiation available upon request |
| Customisation | Device geometry and channel design configurable |
| Documentation | Certificate of Conformity (CoC) available upon request |
