The Smart MCs Cell Harvester is a cell processing device designed for separation and recovery of cells from culture media. It operates using inertial microfluidics, where cells are guided within spiral microchannels based on their biophysical properties, enabling label-free separation from debris, dead cells, and excess liquid.
This system supports continuous processing and is suitable for applications requiring cell concentration and media reduction.
The use of inertial microfluidics for cell separation and processing is demonstrated in published research:
Inertial-Based Filtration Method for Removal of Microcarriers from Mesenchymal Stem Cell Suspensions
Scientific Reports (2018)
https://doi.org/10.1038/s41598-018-31019-y
This study demonstrates the use of inertial focusing in spiral microchannels to separate microcarriers from mesenchymal stem cell (MSC) suspensions. The system enables high-throughput processing, achieving ~94% cell recovery after two passes at flow rates of up to ~30 mL/min.
The results highlight the suitability of inertial microfluidics for cell recovery, sample purification, and bioprocessing applications, particularly where gentle handling and high throughput are required.
| Product Type | Cell harvester / dewatering unit |
|---|---|
| Technology | Inertial microfluidics (spiral microchannels) |
| Separation Method | Label-free, size- and property-based separation |
| Cell Size Range | Effective for cells above ~5–7 µm |
| Processing Mode | Continuous flow |
| Function | Cell concentration and media removal |
| Material | PDMS |
| Sterility | Autoclave and gamma irradiation available upon request |
| Applications | Cell harvesting, volume reduction, bioprocessing |
| Documentation | Certificate of Conformity (CoC) available upon request |
