Microcarrier Innovations: Paving the Way for Large-Scale Mesenchymal Stromal Cell Expansion A recent review published in the Journal of Trends in Biotechnology highlights the critical advancements and challenges in the field of mesenchymal stromal cell (MSC) expansion through microcarrier technology (Read More - DOI: 10.1016/j.tibtech.2024.01.001). With advancements in cellular therapy, the crucial need for [...]
Publication Title: "High-Titer Manufacturing of SARS-CoV-2 Spike-Pseudotyped VSV in Stirred-Tank Bioreactors: A Leap in Vaccine Production Technology". DOI: 10.1016/j.omtm.2024.101189 In a significant advancement for vaccine production technology, a recent article published in the journal of Methods & Clinical Development (Cell Press) has outlined the efficacy of microcarrier systems in stirred-tank bioreactors for the production of [...]
Production of recombinant adeno-associated virus vectors using microcarrier culture of HEK293T cells The study conducted by Yongfa Lan, HaiRui Yang, and QingRui You from Obio Technology, commissioned by Cytiva, presents a comprehensive comparison of producing adeno-associated virus (AAV) using different cell culture methods, specifically focusing on the use of microcarriers versus traditional flask culture [...]
Dive into the world of cell therapy development and manufacturing with the latest episode of Smart Biotech Scientist Podcast with our very own Prof. Steve Oh: This week, David was joined by Steve Oh, Scientific Advisor and ex-A*STAR Professor, who brings a wealth of knowledge from his extensive experience in biotechnology. Steve will offer [...]
As we welcome 2024, we can't help but reflect on the incredible year that was 2023. It was a year marked by significant achievements and milestones for Smart MCs, and we are filled with gratitude for your supports. This past year, Smart MCs had the privilege of serving dozens of customers, each with their [...]
RoosterBio Inc. has published findings that herald a new era in the biomanufacturing of human mesenchymal stem cells (hMSCs). The study focuses on the implementation of microcarrier technology, which has been shown to significantly reduce the costs associated with MSC production. The white paper released by RoosterBio delves into the scalability of MSC cultivation using [...]
Source of Images and article: 10.1186/s13568-019-0794-5 A Study Shows Better Way to Make HEK Cells at large-scale for Gene Therapy and vaccine production Researchers, including Yang and others, have shared a new method that could make it easier to produce important cells used in gene therapy and viral [...]
By 2040, the world is set to witness an unprecedented health challenge. Dry age-related macular degeneration (AMD) is predicted to impact a staggering 300 million individuals globally. In the face of this escalating health crisis and the current lack of viable treatments, hope emerges from ongoing clinical trials. These trials are [...]
In the world of vaccine manufacturing, achieving the highest level of efficiency and consistent output is imperative. Seen especially when addressing the urgent demand for widespread immunisation, combating infectious diseases, and responding to global health crises. An article published by Cell Culture Dish, outlined the recent innovations in accelerating vaccine production from Vero cells [...]
An exciting progression in the world of artificial meat was announced a few days ago as cultured meat products were officially approved by the USDA for commercial sale in the US. The United States Department of Agriculture (USDA) is the US authority responsible for developing laws and approvals surrounding farming, forestry and food. [...]
